This gives you the following starting point for your session: You can choose a template or create your own from scratch. This will give you a screen of options for the session you'll be creating. Start by opening up the application and clicking on "New Session". So this seemed like the perfect application for my needs, and I dug in to get it set up. You can even output it to a recorded file if you'd like. You can choose different inputs and sources, and select the outputs as well for the audio. I looked around and found a few options, but the one that seemed most up to date and current was Audio Hijack by Rogue Amoeba.Įssentially, Audio Hijack does just that: it hijacks the audio on your computer and gives you the option to manipulate it. So I kept on searching, and found some suggestions of using a noise gate program. I found a couple tutorials on noise removal, but they didn't really seem to remove that much noise. It's a great tool, but it wasn't very user friendly. So I started looking for ways to get rid of the hum, and was led to Audacity. The only problem was a small hum, and it wasn't terrible but it did bug me (partly because I'm a perfectionist). Most of the time I'd get it close to right, but not always. So it was really tough to get everything just right. If the external hard drive started running, that was definitely getting picked up. If someone walked across the floor upstairs, that would probably get picked up. If a car drove by outside, that might get picked up. I've been recording courses for Thinkster.io for about a year now, and each time I'd record I'd have to make sure my office was dead silent. Simple, huh? We'll use that in a minute after configuring Audio Hijack. The screen will look like this after you do that:Īnd that's it! You've created your virtual device. At the top of the screen you can give it a name so that it's easy to identify later on. Open Loopback and create a new virtual device. Let's create the virtual device we'll use for Camtasia. In our case, we're just going to create a virtual device that can be used as an output device from Audio Hijack. This allows you to take audio from application A and pass it to audio processing software B. It allows you to capture audio in one (or more) applications and route it to a new virtual input device. Loopback by Rogue Amoeba is a great application to manage audio on your computer. I am by no means an expert, and will continue to play with these programs and settings, but what I have set up now seems to be working great. By the end of this post, you should be able to have everything set up. Using Audio Hijack and Loopback from Rogue Amoeba will help improve the quality of your sound output. The great thing is you don't need to spend a fortune on equipment to get this quality. Your listeners will hear nice crisp audio, and there won't be any fans or anything in the background. A proper setup of the audio on your computer will make for great recording quality.
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Last but certainly not least, a QR code that links directly to a useful image is a lot more straightforward to use than making people navigate to a website and browse for the picture in question. When you’re looking for a zoomable, high-definition image, this can be crucial. Higher qualityĪnother benefit of not having to host your picture online is that it doesn’t need to be converted, which can lead to a loss of quality. Instead of linking to your image hosted on a website or social network, which could go offline or have technical problems at any point, a QR code for pictures links directly to your image, meaning it will remain accessible at all times. PDF417, DataMatrix, QR, and other barcodes from TIF, PDF and other image documents. Decode barcodes in C, VB, Java, CC++, Delphi, PHP and other languages. QR code for pictures actually have some advantages over some types of QR code, such as those that link to a website or social media platform, if your main focus is on sharing a specific photo or graphic. Barcode Reader Software Development Kit (SDK). Mind you, not all codes are created equal. How does the app work Follow the instruction on the screen, take a photo of the QR with your phones camera and voil: we do the math for you and provide. App to provide simple way of scanning all types of Barcodes and QR codes available and also provide. Every QR code consists of a number of black squares and dots which represent certain pieces of information.QR codes have a plethora of uses and are becoming more and more popular every day. It is a machine-scannable image that can instantly be read using a Smartphone camera. Method 1As a built-in under iPhones Photos app. Like any other barcode, a QR code is nothing more than a way to store information in a machine-readable optical label.īasically, a QR code works in the same way as a barcode at the supermarket. QR codes are square barcodes (two-dimensional barcodes) that were first developed and used in Japan. The QR code term stands for Quick Response Code. After selecting the file, it will automatically decode and display the results.If you are using a mobile phone, just take a picture and upload it.Uploading a QR code(image file) for decoding is a stable method.The camera function will be locked and crashed, In my experience, using camera on chrome browser by Android mobile will make a problem,.One quick scan is all it takes to check that a QR code for a text, image or website link. The QR code status is valid for 45 minutes only. AarogyaSetu app does have a reader built-in, but the architecture is such that if any developer wishes to read the signed QR code generated by AarogyaSetu backend to verify users AarogyaSetu status they can do the same in respective apps/platforms. Scan Now Scan QR code from image Drop or choose the QR image Drag & Drop or browse Built with the most used and secure Googles Zxing library. This is to verify the status of Aarogya Setu user. After scanning the QR / Barcode this app decode the text. You can use it online on mobile and desktop also. QRCode and Barcode reader with the ability to turn on / off the rear camera flash and capture the QR from a photo. It helps you scan QR from images and also webcam. I successfully tested this camera feature on chrome browser on PC, QR Scanner Warns you if dangers lie behind a QR code. The QR code scanner online allows you to scan QR codes without any app.After successfully scanning, the result will be displayed on the screen. Aspose QR Code Reader is a free online application to read barcodes from image or your mobile phones camera.If it not doesn't detect your code, move back and forth slightly.Tap the notification to open the link associated. Your device will recognise the QR code and display a notification. Hold your device so that the QR code appears in the viewfinder in the Camera app. Open the Camera app from the Home Screen, Control Centre or Lock Screen.
Lmk what y’all think and how hard the unfinished levels are! I’ll make a much better list when I have more time to spare and figure out how to beat the anurian levels □□□. Maglancia Shores: 8.5 (what just happened) Lightseeker’s Camp: 5.5 (more paths does not equal harder time) Silver oak Outpost: 6 (now we’re getting somewhere) Otil Farmlands: 5 (so much fun but so easy) Gryffon Point: 4.5 (use the griffons or it gets really hard)ĭragon’s Boneyard: 4 (these are 4 cuz ice witches and apex predators annoy me) Kingdom Rush Origins: (I’m starting to understand why no one has done this yet) (Disclaimer I stopped this one at unseelie Court, will finish all games and make a more complete list) Here you will find walkthrough videos and links by the best Kingdom Rush defenders. Sunken Citadel: 9.5 (such a hard level for such an easy boss) Welcome to the Kingdom Rush Frontiers strategy guide and walkthrough section. Temple of Sarqua: 6.5 (using a healthy combo of all non barracks makes this one a breeze)ĭark Descent: 4.5 (easy but so so so much fun)īonesburg: 8 (getting three stars on this one is really tricky imo) Bruxa HELPSĭesecrated Grove: 7.5 (once you figure out bonesburg DG is similar in terms of difficulty) At the end of the day what worked was using this walkthrough, except using two upgraded archers up top instead of three initially, and aggressive selling and establishing upgraded mages on the. On the mobile versions, the first three heroes are free and are unlocked by beating Pagras. All the walkthroughs I found were on a different platform or difficulty level. Kingdom Rush: Top 10 Tips and Cheats You Need to Know. Ma’qua Urqu: 6 (Mechas make the tricksters much easier and cheaper to deal with) The best heroes are Oni for the original Kingdom Rush, Alric for Kingdom Rush: Frontiers, Phoenix the Eternal Bird for Kingdom Rush: Origins, and Doom Tank for Kingdom Rush: Vengeance. I probably tried this level 30 times to do heroic on android, veteran. Lost Jungle: 6.5 (Reapers make things tricky). Nazeru’s Gates: 8 (I can do them now but it took me a good 15 attempts to figure out the early waves of this one) Rotwick: 6.5 (specters make things tricky) Pandemonium: 10 by reputation, unfinished Full Game Leaderboard Level Leaderboard All Southport The Farmlands Pagras Twin Rivers Silveroak Forest The Citadel Coldstep Mines Icewind Pass Stormcloud Temple The Wastes Forsaken Valley The Dark Tower Ruins of Acaroth Hushwood Bandits Lair Sarelgazs Lair Glacial Heights HaKraj Plateau Rotten Forest. Stormcloud Temple: 6 (JT is a tough boss the first couple tries, and his instakill for heroes counters the best free hero in KR)įorsaken Valley: 7 (personally this one is really tough) Twin River Pass: 7.5 (This level on Heroic makes me cry)Ĭoldstep Mines: 5.5 (adjusting to the mines makes this a tad harder than IceWind.) Very fast vicious creatures that can dodge melee attacks.I still have a few levels to beat in the bonus campaigns, but my rankings so far go: Make sure you have enough firepower to support them! You can now upgrade your Towers up to level 2.īarracks are good for blocking the enemy, but lack attack power.
Shockwave has a large selection of fun online and download dress up games. has games for everyone - free online games, free download games and new daily games each week, not to mention game reviews and ratings, a community full of gamers and plenty of exclusive member perks. You'll enjoy unlimited play on all download games, no ad interruptions on all online games and brand new games each week. When you give the code back to us, we know that you’re. If you forget your password, or if someone else is trying to take over your account, we send a verification code to that alternate email or phone number. In addition, the Skorpio X5 offers plenty of scan key options: 2 Side, 1 central, trigger (Pistol version) or bottom (HH version), plus a Soft Spot allowing. Far more quickly than anyone could have imagined. Security info is an alternate contact email address or phone number that you add to your account. What started as a place for people in the know to download software became the place to download software on the burgeoning Internet. If you're a gamer looking for some serious fun, join Shockwave® UNLIMITED and receive access to exclusive online games and downloads for a low monthly fee. The shareware downloads bulletin board system (BBS) that would become Tucows Downloads was founded back in 1993 on a library computer in Flint, MI. Best of all, is updated daily, making our library of games virtually endless! is the ultimate destination for free online games, free download games, and more! This is your chance to play games 24-7, with a ton of great categories to choose from - Action Games, Adventure Games, Card & Board Games, Jigsaws Games, Kids & Family Games, Music & Photos Games, Puzzle Games, Racing Games, Shooter Games, Sports Games, Strategy Games, Word Games, and more. Ombre powder brow shading pigmentation is more dominant at the tail fading towards the head of the brow. While microblading alone can look natural and understated, an ombre powder brow can make the brow stand out, structuring the brow and making it more of a statement. Shading is not hair strokes but tiny dots of color (or pigmentation) This added color or pigmentation will make a brow more defined and dramatic and may mimic a makeup powder or pomade. This blanket of color creates color density or “fill” that gives the brows definition. A shading machine is used to add soft layers of pigmentation that provide a blanket of color over the brows. Shading is different from the microblading technique. The density and color depth can be added for unsure clients. Two treatments are required to bring the brows to their result adjusting color density and depth during the second treatment/Touchup. It is our experience at BrowBeat that people use the word “natural” when they mean: “Please don’t let my brows look like a tattoo.”ĭo not be afraid of ombre powder brows if you prefer definition. Defined brows that make a statement are popular due to icons such as Kim Kardashian and Lady Gaga. May result in loss of pigmentation after healing.The desire for crisper lines and deeper pigmentation is growing. Failure to do so will result in excessive bruising, swelling, and bleeding during and after the procedure. Do not consume any alcohol beverages, medication, or caffeine 24 hours before your appointment. If you have had any surgical procedures such as: blepharoplasty, rhinoplasty, eye surgery, eye lift, and etc done on the face area, please wait THREE MONTHS to fully heal before getting another procedure done.Ĭannot be under the influence of drugs and alcohol. No diabetes, high blood pressure, or mitral valve disorder.Īnyone who has anxiety or on anxiety medication.Īnyone who had experience seizures and are on medication for it.Īny radiotherapy or chemotherapy must consult with your physician before booking an appointment.Ĭannot be allergic to pigmentation, makeup, epinephrine, and lidocaine.Īnyone who had prior experience with inflammatory hyper-pigmentation. Failure to do so and still show up will result in automatic reschedule and will be sent home.Ĭannot be on any skin medication such as steroids - which causes the skin to become more sensitive during the procedure.Ĭannot have eczema or psoriasis on the procedure area. If there are any unexpected flare-ups, you must contact me IMMEDIATELY to reschedule. No acne, blisters, rashes, bruises, scars, or any other types of undiagnosed open wounds on the procedure area. Must be off Retin-A, Retinol, Fish oil, or any types of blood thinner ONE WEEK before getting a service done. You must be off Accutane for ONE YEAR before getting brow service. You must wait until you are completely done with nursing before getting any form of tattoo.Ĭannot have any transmittable blood conditions such as: HIV, AIDS, Hepatitis, and etc. Must not be under the age of 18 years of age, unless parent written consent.Ĭannot be pregnant/nursing. Please contact me directly if you have any questions or concerns. Any person with one of the following conditions may NOT be good candidates for cosmetic tattooing. Here, you will even color the documents and even draw perfect shapes and lines using the Shapes Tool. From moving to rotating your handwriting, there is a lot that you can do to your documents when using this app. This app allows you to do many things that you c cannot do with an analog paper. Helps you escape the limits of an analog paper.Finally, you will manage to create custom outlines for easy navigation through your documents. You will mark those documents that matter to you as a favorite so that you can access them with precision. This app will help you organize your documents in folders and even allow you to create unlimited subfolders. This app can also help you scan documents and even recognize text. Besides this, you will be able to export these documents and even share them with your friends out there. Used to track the information of the embedded YouTube videos on a website.When using this app, you will import word, images, PowerPoint, PDF, and even photos right on your device. The purpose of the cookie is to determine if the user's browser supports cookies. This is used to present users with ads that are relevant to them according to the user profile. Used by Google DoubleClick and stores information about how the user uses the website and any other advertisement before visiting the website. The cookie also tracks the behavior of the user across the web on sites that have Facebook pixel or Facebook social plugin. The cookie is set by Facebook to show relevant advertisments to the users and measure and improve the advertisements. This cookie is set by Facebook to deliver advertisement when they are on Facebook or a digital platform powered by Facebook advertising after visiting this website. These cookies track visitors across websites and collect information to provide customized ads. It does not store any personal data.Īdvertisement cookies are used to provide visitors with relevant ads and marketing campaigns. The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. The cookie is used to store the user consent for the cookies in the category "Performance". This cookie is set by GDPR Cookie Consent plugin. The cookies is used to store the user consent for the cookies in the category "Necessary". 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Visitors will be welcomed into a glazed central plaza containing full-height trees, before ascending in panoramic elevators to a viewing platform on the highest floor. The 53-story building was designed by Foster+Partners to accommodate premium office accommodation connected by an underground link to the adjacent Warsaw Central Station. The 310-metre Varso Tower in Warsaw will become the tallest tower in the European Union upon its completion, narrowly surpassing The Shard in London. The tower appears to comprise two separate parts that intertwine as they reach upwards, reflecting the close relationship between China and nearby Hong Kong. The 330-metre building designed by global architecture firm Gensler features a subtly twisting design that gives it a unique appearance and helps to disperse powerful gusts of wind. In the booming Chinese city of Shenzhen, this mixed-use high rise occupies a prominent position in the new Qianhai financial district. The upper floors will accommodate the Waldorf Astoria Hotel alongside public observation decks looking out across the city to the mountains and ocean beyond. The design by American firm Kohn Pedersen Fox Associates comprises a layered composition of glazed boxes intend to form a vertical city containing a range of public and private functions. At a height of 335 metres, it will become the Indonesian capital’s first supertall skyscraper. Tower 1 is the main landmark of the Thamrin Nine Development in downtown Jakarta. The 375-metre-tall tower will contain a mixture of offices and residential units, with a retail podium at the base bordering a new public plaza. The layered form was inspired by the overlapping petals of the bougainvillea flower. The tower designed by Kohn Pedersen Fox Associates features four overlapping facade screens that taper slightly towards the top. The 382-metre tower designed by as part of the masterplan by HKR Architects will become the central beacon for the new urban district.īack to China, where the Shenzhen Center is rising high above the city’s Great China International Exchange Square. The project comprises five towers and a retail podium, with one of the towers set to become the tallest building in the Commonwealth of Independent States formed by the former Soviet Republics. The design credited to Buruoj Engineering Consultancy is notable for its twisting form and it is claimed that, once completed, it will be the only building in the world to twist a full 360 degrees along its height.Ību Dhabi Plaza is a mixed-use development taking shape in the Kazakh capital, Nur-Sultan. If it does, the 93-story tower will become the second tallest building in Saudi Arabia and one of the tallest residential buildings in the world. Its bevelled silhouette references the bud of the Yulan magnolia and it is topped with a symbolic lantern.ĭetails are sparse about the projects currently under construction in Saudi Arabia, but while we await updates on the progress of Jeddah Tower, it appears this 432-metre residential supertall is likely to top out in 2020. The design by global architecture firm 5+design is inspired by Dongguan’s natural surroundings in the Pearl River Delta, and the building is situated to provide a direct line of sight to the nearby Huanggi Mountain. Part of a complex of five separate buildings in downtown Dongguan, this 432-metre tower will rise above a six-story retail podium containing stores and restaurants. As with Jeddah Tower, the project has been beset by a raft of problems, including the need to scale down its proposed height to 475 metres due to airspace regulations. It might seem naive to keep including this tower in Shanghai in our list, but following a recent suspension of construction work, progress is set to resume and the tower may yet reach its full height in 2020. However, recent noises hint that construction may be stepped up in the coming months so there remains a possibility that the building designed by Adrian Smith + Gordon Gill Architecture might reach its final height of around 1,000 metres by the end of the year. Could this be the year that the tallest manmade structure of all time finally tops out? Construction of the Jeddah Tower in Saudi Arabia has been plagued by political, economic and labour issues, with the proposed completion date of 2020 deemed unrealistic for many years now. For those looking for one of the best PuTTY alternatives for Mac, Chrome Secure Shell is the right choice It’s a terminal emulator and SSH client designed for Chrome. Price: free trial available pro version starts from € 39.00. This tool is appropriate for use in Windows, Linux, and Mac OS. This is the second widely used SSH connectivity tools that are available as an open source version on the web. Solar Putty Download 2) Open SSH Open SSH – Top 10 Best Free Open Source SSH Clients for Windows Linux and MacOS – HostNamaste. Then, use the following command to convert the.ppk format private key to a standard PEM format private key: puttygen privatekey.ppk -O private-openssh -o privatekey.pem. This will also install the command-line version of puttygen, the PuTTY key generator tool. First, install PuTTY for Mac using brew install putty or port install putty (see below). After that find the terminal which supports SSH connections to remote servers. To utilize it, go to Finder and then opt for Go - utilities from the top menu. Mac OS has a built-in command-line SSH client known as Terminal. Below is the detailed guide to download PuTTYgen on Mac operating system. Termius does have a Basic version that is free, but without the SFTP GUI, it’s pretty similar to the other options on our list.Download PuTTYgen for Mac. To get the SFTP feature, though, you need to pay $8.33 per month for the Premium version of Termius. This, in our view, makes Termius an easier SSH client to understand and use than many options on this list. So you can upload and download files via an SSH connection in Termius without needing to use command line! In addition to Terminal-like windows and controls, Termius has a GUI for SFTP (Secure File Transfer Protocol), a secure method of sharing files between devices. Termius isn’t a Terminal replacement like iTerm2, but it does have a similar autocomplete feature for typing out command line text, as well as the ability to save frequently used commands, which you can share with others on the SSH server. This means it’s a solid method for encrypting and sending data between devices you own, as well as any remote devices you need to access. So you can use it to connect to SSH servers on your Mac, but also on your iOS devices. Termius is an SSH client that works not only on Mac, Windows, and Linux computers, but also on mobile devices. But if you want to learn Terminal-and have a little help with it through an autocomplete feature-iTerm2 could be a great Mac SSH client, though it might spoil you with its many great features. It may have a bit of a learning curve if you don’t know Terminal commands fairly well already. With autocomplete code options (which work in SSH connections and in normal Terminal windows) and the ability to pull up the application with a hotkey, iTerm2’s features are incredible for making and utilizing SSH connections, and for completing Terminal functions in general. And it lets you set up and quickly switch between profiles, so you can utilize different permission levels or quickly go to different SSH connections. ITerm2 also keeps track of which directories you visit most often on your SSH connections, so you can get into them again much faster. In terms of SSH, iTerm2 will keep you informed of which directory you’re in, and will let you navigate back to previous commands by hitting Shift + Cmd + Up or Shift + Cmd + Down. It also lets you go back and recover text you deleted or changed with an Instant Replay feature. Copying and pasting in iTerm2 is a lot easier than it is in PuTTY for Mac, and it keeps a paste history for you so you can quickly find the second-to-last item you copied. Here’s the part of the raid that still tickles me immensely. I suspect that a big chunk of what we’ll see with Eden is tied into that… and I also suspect that Eden has more to do with dimension-hopping than has been heretofore revealed. We have a lot of places we can go at this point, and that’s excellent, but it also means that we’re stuck in a place wherein any given direction feels plausible. Of course, that also ties into the big unanswered question of the end of the MSQ. I have to admit, though, part of me was really thinking that Nero was going to show up right at the end there. By taking control of it and then successfully proving that the initial plan behind its mechanics can work, we’ve already got a template for restoring the remaining four elements, even though it’s obvious just from story structure that there’ll be more than that before all is said and done. We start off not just with the obvious MSQ victory under our belt, but with two pretty major wins kicking off Eden. I don’t want to call it predictable, but the whole point of having these mysteries set up is that we don’t know the answers and can’t wholly figure them out yet.Įqually interesting is the set of story conceits going into this series. This raises further questions vis-a-vis the Ascians and the very nature of what we’ve been doing on the First, questions that will no doubt be answered… oh, around the time that patch 5.4 rolls around and we get the end of this particular series. It’s a reservoir, a repository, like it was just storing everything up to be used later. In other words, it seems to be the herald of the Flood of Light, but we also still don’t know everything that we would perhaps like to know about the causes behind the Flood of Light.Īs we’ve seen so far, Eden doesn’t appear to actually have much in the way of a will. Eden is hardly the first of the Sin Eaters, nor is it really tied to them, but there’s also something interesting going on with the way that it seems to have been responsible for the cessation of the flow of aether in the larger world. I had some predictions about where we’d be going with the story of Eden ahead of time, but as before, it seems as if the story at this point has raised more questions than were answered. (And there will be soft spoilers for the raid story, so if you’d like to avoid those, be fairly warned.) That sure is one heck of a raid series to start things off let’s talk about it a little bit. Play Final Fantasy XIVAnd then I remember that I’m discussing being halfway done with leveling in an expansion that launched not even a month ago and that puts things back in perspective. Tung, Ken Berglund, Claire-Anne Gutekunst, Ute Hochgeschwender, Robert E. Development of Timd2 as a reporter gene for MRI. Cell Communication and Signaling 2016, 14 Transferring intercellular signals and traits between cancer cells: extracellular vesicles as “homing pigeons”. Giulia Cesi, Geoffroy Walbrecq, Christiane Margue, Stephanie Kreis.Tracking Extracellular Vesicles Delivery and RNA Translation Using Multiplexed Reporters. Anthony Yan-Tang Wu, Charles Pin-Kuang Lai.Periodic Mesoporous Organosilica Coated Prussian Blue for MR/PA Dual-Modal Imaging-Guided Photothermal-Chemotherapy of Triple Negative Breast Cancer. Wei Tian, Yunyan Su, Ying Tian, Shouju Wang, Xiaodan Su, Ying Liu, Yunlei Zhang, Yuxia Tang, Qianqian Ni, Wenfei Liu, Meng Dang, Chunyan Wang, Junjie Zhang, Zhaogang Teng, Guangming Lu.Imaging of anticancer drug action in single cells. Hybrid Nanodots for Efficient Cancer Theranostics. Xiaoyan Lv, Xue Wang, Ting Li, Chaogang Wei, Yong'an Tang, Tao Yang, Qiaoli Wang, Xiangliang Yang, Huabing Chen, Junkang Shen, Hong Yang, Hengte Ke.Methods for Systematic Identification of Membrane Proteins for Specific Capture of Cancer-Derived Extracellular Vesicles. Birrer, Ralph Weissleder, Hakho Lee, Xandra O. Tannous, Charles Pin-Kuang Lai, Michael J. Mikołaj Piotr Zaborowski, Kyungheon Lee, Young Jeong Na, Alessandro Sammarco, Xuan Zhang, Marcin Iwanicki, Pike See Cheah, Hsing-Ying Lin, Max Zinter, Chung-Yu Chou, Giulia Fulci, Bakhos A.A Cell-Specific Nuclear Factor-Kappa B–Activating Gene Expression Strategy for Delivering Cancer Immunotherapy. Nanoparticles-mediated Brain Imaging and Disease Prognosis by Conventional as well as Modern Modal Imaging Techniques: a Comparison. Singh, Aman Chandra Kaushik, Jyotsna Sharma, Zheng-Jing Long, Zhi-Hong Wen, Sunil Kumar Mishra, Chung-Kun Yen, Ravi Kumar Chaudhary, Yow-Ling Shiue. Cheng-Tang Pan, Wei-Hsi Chang, Ajay Kumar, Satya P.Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles. Schweiger, Charles Pin- Kuang Lai, Ralph Weissleder, Hakho Lee, Kasey C. Allen, Purva Rumde, Bence György, Massimo Aufiero, Markus W. Mikołaj Piotr Zaborowski, Pike See Cheah, Xuan Zhang, Isabella Bushko, Kyungheon Lee, Alessandro Sammarco, Valentina Zappulli, Sybren Lein Nikola Maas, Ryan M.Ag2S nanoparticles as an emerging single-component theranostic agent. Ruxia Han, Jinrong Peng, Yao Xiao, Ying Hao, Yanpeng Jia, Zhiyong Qian.Technologies and Standardization in Research on Extracellular Vesicles. Nocera, Sarath Chandra Alli, Lara Milane, Alan Zimmerman, Mansoor Amiji, Alexander R. Srujan Gandham, Xianyi Su, Jacqueline Wood, Angela L.Archives of Computational Methods in Engineering 2021, 28 Trends of Multimodal Neural Engineering Study: A Bibliometric Review. Jiaming Wang, Rui Cheng, Pin-Chao Liao.Radioimaging of Activated T Cells in Preclinical and Clinical Cancer Investigations. Intravital microscopy for real-time monitoring of drug delivery and nanobiological processes. Jeffrey Momoh, Dimitrios Kapsokalyvas, Michael Vogt, Sjoerd Hak, Fabian Kiessling, Marc van Zandvoort, Twan Lammers, Alexandros Marios Sofias.One-Step Solvothermal Synthesis of Targetable Optomagnetic Upconversion Nanoparticles for in Vivo Bimodal Imaging. Xu Wang, Jia-Tong Chen, Haomiao Zhu, Xueyuan Chen, and Xiu-Ping Yan.Dynamic Biodistribution of Extracellular Vesicles in Vivo Using a Multimodal Imaging Reporter. Lai, Osama Mardini, Maria Ericsson, Shilpa Prabhakar, Casey A. Lanthanide Probes for Bioresponsive Imaging. Journal of the American Chemical Society 2015, 137 Single 19F Probe for Simultaneous Detection of Multiple Metal Ions Using miCEST MRI. This article is cited by 37 publications. This work shows for the first time a single small reporter (∼40 kDa) which can be monitored with most available molecular imaging modalities and can be extended for single cell imaging using intravital microscopy, allowing real-time tracking of any cell expressing it in vivo. Moreover, single photon emission computed tomography showed enhanced imaging of these tumors upon injection with streptavidin complexed to 111In-DTPA-biotin. Brain tumors expressing this reporter had high sensitivity for detection by magnetic resonance and fluorescence tomographic imaging upon injection of streptavidin conjugated to magnetic nanoparticles or fluorophore, respectively. We engineered glioma cells to express this reporter and showed that brain tumor formation can be temporally imaged by bioluminescence following systemic administration of coelenterazine. A metabolically biotinylated, membrane-bound form of Gaussia luciferase was synthesized, termed mbGluc-biotin. We have developed a multifaceted, highly specific reporter for multimodal in vivo imaging and applied it for detection of brain tumors. |
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