![]() Tung, Ken Berglund, Claire-Anne Gutekunst, Ute Hochgeschwender, Robert E. Development of Timd2 as a reporter gene for MRI. Cell Communication and Signaling 2016, 14 Transferring intercellular signals and traits between cancer cells: extracellular vesicles as “homing pigeons”. Giulia Cesi, Geoffroy Walbrecq, Christiane Margue, Stephanie Kreis.Tracking Extracellular Vesicles Delivery and RNA Translation Using Multiplexed Reporters. Anthony Yan-Tang Wu, Charles Pin-Kuang Lai.Periodic Mesoporous Organosilica Coated Prussian Blue for MR/PA Dual-Modal Imaging-Guided Photothermal-Chemotherapy of Triple Negative Breast Cancer. Wei Tian, Yunyan Su, Ying Tian, Shouju Wang, Xiaodan Su, Ying Liu, Yunlei Zhang, Yuxia Tang, Qianqian Ni, Wenfei Liu, Meng Dang, Chunyan Wang, Junjie Zhang, Zhaogang Teng, Guangming Lu.Imaging of anticancer drug action in single cells. Hybrid Nanodots for Efficient Cancer Theranostics. Xiaoyan Lv, Xue Wang, Ting Li, Chaogang Wei, Yong'an Tang, Tao Yang, Qiaoli Wang, Xiangliang Yang, Huabing Chen, Junkang Shen, Hong Yang, Hengte Ke.Methods for Systematic Identification of Membrane Proteins for Specific Capture of Cancer-Derived Extracellular Vesicles. Birrer, Ralph Weissleder, Hakho Lee, Xandra O. Tannous, Charles Pin-Kuang Lai, Michael J. Mikołaj Piotr Zaborowski, Kyungheon Lee, Young Jeong Na, Alessandro Sammarco, Xuan Zhang, Marcin Iwanicki, Pike See Cheah, Hsing-Ying Lin, Max Zinter, Chung-Yu Chou, Giulia Fulci, Bakhos A.A Cell-Specific Nuclear Factor-Kappa B–Activating Gene Expression Strategy for Delivering Cancer Immunotherapy. Nanoparticles-mediated Brain Imaging and Disease Prognosis by Conventional as well as Modern Modal Imaging Techniques: a Comparison. Singh, Aman Chandra Kaushik, Jyotsna Sharma, Zheng-Jing Long, Zhi-Hong Wen, Sunil Kumar Mishra, Chung-Kun Yen, Ravi Kumar Chaudhary, Yow-Ling Shiue. Cheng-Tang Pan, Wei-Hsi Chang, Ajay Kumar, Satya P.Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles. Schweiger, Charles Pin- Kuang Lai, Ralph Weissleder, Hakho Lee, Kasey C. Allen, Purva Rumde, Bence György, Massimo Aufiero, Markus W. Mikołaj Piotr Zaborowski, Pike See Cheah, Xuan Zhang, Isabella Bushko, Kyungheon Lee, Alessandro Sammarco, Valentina Zappulli, Sybren Lein Nikola Maas, Ryan M.Ag2S nanoparticles as an emerging single-component theranostic agent. Ruxia Han, Jinrong Peng, Yao Xiao, Ying Hao, Yanpeng Jia, Zhiyong Qian.Technologies and Standardization in Research on Extracellular Vesicles. Nocera, Sarath Chandra Alli, Lara Milane, Alan Zimmerman, Mansoor Amiji, Alexander R. Srujan Gandham, Xianyi Su, Jacqueline Wood, Angela L.Archives of Computational Methods in Engineering 2021, 28 Trends of Multimodal Neural Engineering Study: A Bibliometric Review. Jiaming Wang, Rui Cheng, Pin-Chao Liao.Radioimaging of Activated T Cells in Preclinical and Clinical Cancer Investigations. Intravital microscopy for real-time monitoring of drug delivery and nanobiological processes. Jeffrey Momoh, Dimitrios Kapsokalyvas, Michael Vogt, Sjoerd Hak, Fabian Kiessling, Marc van Zandvoort, Twan Lammers, Alexandros Marios Sofias.One-Step Solvothermal Synthesis of Targetable Optomagnetic Upconversion Nanoparticles for in Vivo Bimodal Imaging. Xu Wang, Jia-Tong Chen, Haomiao Zhu, Xueyuan Chen, and Xiu-Ping Yan.Dynamic Biodistribution of Extracellular Vesicles in Vivo Using a Multimodal Imaging Reporter. Lai, Osama Mardini, Maria Ericsson, Shilpa Prabhakar, Casey A. ![]() Lanthanide Probes for Bioresponsive Imaging. Journal of the American Chemical Society 2015, 137 Single 19F Probe for Simultaneous Detection of Multiple Metal Ions Using miCEST MRI. This article is cited by 37 publications. This work shows for the first time a single small reporter (∼40 kDa) which can be monitored with most available molecular imaging modalities and can be extended for single cell imaging using intravital microscopy, allowing real-time tracking of any cell expressing it in vivo. Moreover, single photon emission computed tomography showed enhanced imaging of these tumors upon injection with streptavidin complexed to 111In-DTPA-biotin. ![]() Brain tumors expressing this reporter had high sensitivity for detection by magnetic resonance and fluorescence tomographic imaging upon injection of streptavidin conjugated to magnetic nanoparticles or fluorophore, respectively. We engineered glioma cells to express this reporter and showed that brain tumor formation can be temporally imaged by bioluminescence following systemic administration of coelenterazine. A metabolically biotinylated, membrane-bound form of Gaussia luciferase was synthesized, termed mbGluc-biotin. We have developed a multifaceted, highly specific reporter for multimodal in vivo imaging and applied it for detection of brain tumors.
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